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An allergic reaction contact dermatitis usually begins within hours to days after exposure to nickel. The reaction may last as long as 2 to 4 weeks. The reaction tends to occur only where your skin came into contact with nickel, but sometimes may appear in other places on your body. If you have a skin rash and don't know how you got it, talk to your doctor. If you've already been diagnosed with nickel allergy and are sure you're reacting to nickel exposure, use the over-the-counter treatments and home remedies your doctor has previously recommended. However, if these treatments don't help, call your doctor. If you think the area may have become infected, see your doctor right away.
Signs and symptoms that might indicate an infection include:. Nickel allergy is a condition in which contact with items containing nickel causes an itchy rash and possibly blisters at the site of contact. The top photo shows a positive patch test on the left , after a patch containing nickel was left on the skin for 48 hours. The lower photo shows nickel allergy from metal in clothing, such as a belt buckle. The exact cause of nickel allergy is unknown. As with other allergies, nickel allergy develops when your immune system views nickel as a harmful, rather than harmless substance.
Normally, your immune system only reacts to protect your body against bacteria, viruses or toxic substances. Once your body has developed a reaction to a particular agent allergen — in this case, nickel — your immune system will always be sensitive to it. That means anytime you come into contact with nickel, your immune system will respond and produce an allergic response. Your immune system's sensitivity to nickel may develop after your first exposure or after repeated or prolonged exposure. Some extremely sensitive people may be affected by nickel-containing foods.
Some foods that contain high amounts of nickel include soy products, peas, canned foods, cocoa powder, clams and cashews. Working with metal. If you work in an occupation that constantly exposes you to nickel, your risk of developing an allergy may be higher than it is for someone who doesn't work with the metal. In addition, people who have regular exposure to nickel while doing "wet work" — as a result of either sweat or frequent contact with water — may be more likely to develop nickel allergy. These people may include bartenders, people who work in certain food industries and domestic cleaners. Other people who may have an increased risk of nickel allergy include metalworkers, tailors and hairdressers. Metin, L. Ozkar Bis 1,5-cyclooctadiene nickel 0.
Inorganic Syntheses. Williams; Anthony C. Jones; Jamie F. Bickley; Alexander Steiner; Hywel O. Davies; Timothy J. Leedham; Susan A. Journal of Materials Chemistry. Journal of Organometallic Chemistry. Journal of the American Chemical Society. PMC PMID Nickel compounds. Salts and covalent derivatives of the acetylacetonate ion. Categories : Nickel complexes Acetylacetonate complexes. Other names Ni acac 2 , nickel acac.
EC Number. GHS labelling :. H , H , H , H H acac. Al acac 3. Ti acac 2 Cl 2 Ti acac 3. V acac 3 VO acac 2. Cr acac 2 Cr acac 3. Fe acac 2 Fe acac 3. Co acac 3. Cu acac 2. Ga acac 3. Zr acac 4. Ru acac 3. Rh acac CO 2 Rh acac 3. Pd acac 2. Advertising revenue supports our not-for-profit mission. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. This content does not have an English version. This content does not have an Arabic version. Overview Nickel allergy is a common cause of allergic contact dermatitis — an itchy rash that appears where your skin touches a usually harmless substance. Request an appointment. Nickel allergy Enlarge image Close. Nickel allergy Nickel allergy is a condition in which contact with items containing nickel causes an itchy rash and possibly blisters at the site of contact.
By Mayo Clinic Staff. Share on: Facebook Twitter. Show references Tramontana M, et al. Nickel allergy: Epidemiology, pathomechanism, clinical patterns, treatment and prevention programs. Nickel allergy. American Osteopathic College of Dermatology. Accessed April 30, Nickel allergy: How to avoid exposure and reduce symptoms. American Academy of Dermatology. Burks AW, et al. Contact dermatitis. In: Middleton's Allergy: Principles and Practice. Elsevier; Ahlstrom MG, et al. Nickel allergy and allergic contact dermatitis: A clinical review of immunology, epidemiology, exposure, and treatment.
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